2024知到答案 药理学（南开大学） 完整智慧树网课章节测试答案
第一章 单元测试
文章目录
1、单选题：
Which of the following drugs is an inducer of CYP1A2 ( )
选项：
A:Fluconazole
B:Simvastatin
C:Tobacco
D:Ciprofloxacin
答案: 【Tobacco】
2、单选题：
The process of renal excretion of drugs does not include which of the following options ( )
选项：
A:Hepatoenteric circulation
B:Glomerular filtration
C:Active secretion of renal tubules
D:passive tubule reabsorption
答案: 【Hepatoenteric circulation】
3、单选题：
Which of the following statements is false ( )
选项：
A:Tmax refers to the time that takes a drug or other substance to reach the maximum concentration Cmax
B:T half （T1/2）of a drug refers to the time required for the plasma concentration of the drug to drop by half
C:AUC refers to Area under the curve (pharmacokinetics), regarding plasma drug concentration-time curves
D:The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously
答案: 【The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously】
4、多选题：
The main factors affecting drug absorption are ( )
选项：
A:The first pass effect
B:pH value
C:Blood flow
D:Administration route
答案: 【The first pass effect;
pH value;
Blood flow;
Administration route】
5、单选题：
The bioavailability of the drug refers to （ ）
选项：
A:The fraction or percentage of a drug that reaches hepatic portal circulation
B:The relative speed of the drug absorption into the body
C:The fraction or percentage of a drug that reaches systemic circulation
D:The fraction or percentage of a drug that reaches the action point
答案: 【The fraction or percentage of a drug that reaches systemic circulation】
第二章 单元测试
1、单选题：
Which of the following options is wrong about the antagonist ( )
选项：
A:Antagonists are drugs that decrease or oppose the actions of another drug or endogenous ligand
B:A competitive antagonist binds to the different site as the endogenous signaling molecule, blocking its binding site at the receptor
C:Antagonist have binding affinity to receptor but they have no intrinsic activit
D:Antagonist are typically classified as competitive and non-competitiv
答案: 【A competitive antagonist binds to the different site as the endogenous signaling molecule, blocking its binding site at the receptor】
2、单选题：
Which of the following statements is wrong （ ）
选项：
A:The higher the therapeutic index, the safer the drug, as the risk of a toxic or lethal overdose decreas
B:Effective dose (ED) refers to the minimal drug amount required to achieve the maximum effect
C:The ratio of ED50 to LD50 is termed the therapeutic index and differs for each drug
D:The potency not only depends on the efficacy of a drug, but also on its binding affinity at the target site
答案: 【The ratio of ED50 to LD50 is termed the therapeutic index and differs for each drug】
3、单选题：
The therapeutic index refers to （ ）
选项：
A:ED95/LD5
B:ED50/LD5
C:LD5/ED95
D:LD50/ED50
答案: 【LD50/ED50】
4、单选题：
If a drug binds to a receptor and produces some biologic responses that mimics the response to the endogenous ligand, the drug belongs to ( )
选项：
A:Inhibitor
B:Antagonist
C:Agonist
D:Stimulant
答案: 【Agonist】
5、单选题：
Which of the following statements about the receptor is correct?
选项：
A:Receptor refers to a protein that binds to a ligand and produces a measurable response
B:Receptors are polysaccharides on the cell membrane
C:The effects caused by the binding of receptors and ligands or agonists are excitatory effects
D:All drugs work by stimulating or blocking the corresponding receptors
答案: 【Receptor refers to a protein that binds to a ligand and produces a measurable response】