MOOC 医用细胞生物学(甘肃中医药大学)1462283169 最新慕课完整章节测试答案

Biomembrane Structure-test

1、单选题：
All the following statements describe biomembranes except:​‏​
选项：
A: Different biomembranes may contain different proportions of the same phospholipids.
B:  The two leaflets of a biomembrane may contain different phospholipids.
C:  Some biomembranes have free edges.
D: Some phospholipids and cholesterol may cluster to form lipid rafts.  
答案: 【  Some biomembranes have free edges.】

2、单选题：
‏ The major site of lipid synthesis in eukaryotic cells is the‌
选项：
A: Nucleus
B: Endoplasmic reticulum
C: Mitochondria
D: Cell membrane
答案: 【 Endoplasmic reticulum】

3、单选题：
Phospholipids with short or unsaturated fatty acyl chains‎‎
选项：
A: decrease membrane fluidity.
B: increase membrane fluidity.
C:  cause biomembranes to become thicker
D: allow hydrophilic molecules to diffuse across the lipid bilayer.
答案: 【 increase membrane fluidity.】

4、单选题：
 The _______ are transmembrane proteins.‍‍
选项：
A: lipid-anchored membrane proteins
B: integral membrane proteins
C: peripheral membrane proteins
D: extracellular matrix proteins
答案: 【 integral membrane proteins】

5、单选题：
Glycolipids and glycoproteins are especially abundant in the‏
选项：
A:  nucleus.
B: mitochondrial inner membrane
C: cytosol
D: plasma membrane
答案: 【 plasma membrane】

6、单选题：
Phosphate containing lipids include all of the following except ‌
选项：
A:  phospholipids.
B: sphingolipid
C: triglyceride
D: phosphatidylinositol
答案: 【 triglyceride】

7、判断题：
‏A lipid bilayer is the fundamental structural component of all cell membranes.‌‏‌
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
‍Maintenance of the lipid bilayer in the plasma membrane requires special enzymes and the hydrolysis of ATP.‎‍‎
选项：
A: 正确
B: 错误
答案: 【 错误】

9、填空题：
‏The most abundant lipids in cell membranes are ________________.‏‏‏
答案: 【 phospholipids】

10、填空题：
​Sugar-containing lipids called ____________ are found only in the outer half of the bilayer and their sugar groups are exposed ac the cell surface.‏​‏
答案: 【 glycolipids】

Cell organization and movement I Microfilament

1、单选题：
Within an actin filament, each actin subunit is surrounded by _______ neighboring actin subunits‌
选项：
A: a. one
B: b. two
C: c. four
D: d. eight
答案: 【 c. four】

2、单选题：
During treadmilling, actin subunits ad‌
选项：
A: a. predominantly to filament (+) ends.
B: b. predominantly to filament (−) ends.
C: c. equally to both filament ends.
D: d. along the length of filaments.
答案: 【 a. predominantly to filament (+) ends.】

3、单选题：
 Listeria is a bacteria parasite that has evolved unique ways to enter animal cells and then use actin polymerization for its intracellular movement.  Which of the following statements is true in regards to Listeria and actin polymerization?‍
选项：
A: a. Listeria ActA protein binds and inactivates the Arp2/3 complex.
B: b. Listeria ActA binds VASP, which enhances ATP-actin assembly.
C: c. Cofilin is necessary to accelerate the assembly of the (−) end of the filament.
D: d. CapZ promotes the elongation of the filament.
答案: 【 b. Listeria ActA binds VASP, which enhances ATP-actin assembly.】

4、单选题：
 ‎Which of the following properties is not shared by all myosins?‎
选项：
A: a. the ability to bind ATP
B: d. the presence of a head domain
C: b. the ability to form dimers
D: c. the ability to bind actin
答案: 【 b. the ability to form dimers】

5、单选题：
What is the function of CapZ and tropomodulin in the sacromere?‍
选项：
A: a. to center myosin thick filaments
B: b. to attach actin thin filaments to the Z disk
C: c. to maintain a constant actin thin filament length
D: d. to make contraction sensitive to Ca2+ 
答案: 【 c. to maintain a constant actin thin filament length】

6、单选题：
Gelsolin is activatikred by‌
选项：
A: a. ATP-binding.
B: d. dephosphorylation.
C: c. Ca2+-binding.
D: b. phosphorylation.
答案: 【 c. Ca2+-binding.】

7、单选题：
13. Which region of myosin interacts with actin filaments?‍
选项：
A: a. the head domain
B: b. the rod domain
C: c. the light chains
D: d. the tail domain
答案: 【 a. the head domain】

8、单选题：
Which of the following proteins is involved in formation of actin bundles in microvilli by providing crosslinks between actin filaments‍
选项：
A: a. a actinin
B: b. cofilin
C: c. fimbrin
D: d. profilin
答案: 【 c. fimbrin】

Cell organization and movement II Microtubules and intermediate filament单元测验

1、单选题：
​A microtubule protofilament is formed by the‍
选项：
A: lateral association of only g-tubulin subunits.
B: head-to-tail association of only g-tubulin subunits
C: lateral association of tubulin dimers.
D: head-to-tail association of tubulin dimers.
答案: 【 head-to-tail association of tubulin dimers.】

2、单选题：
 Growing microtubule ends are normally stabilized by  ​
选项：
A: g-tubulin.
B: a GDP cap.
C: phosphorylation of tubulin subunits.
D: a GTP cap.
答案: 【 a GTP cap.】

3、单选题：
All of the following statements describe Kinesin I except‌
选项：
A: Kinesin I is a (−) end-directed motor.
B: Kinesin I transports vesicles along microtubules.
C: Kinesin I binds and hydrolyzes ATP to produce movement.
D: Kinesin I is composed of two heavy chains and two light chains.
答案: 【 Kinesin I is a (−) end-directed motor.】

4、单选题：
The force for axoneme bending is derived from the‏
选项：
A: sliding movement of central pair microtubules.
B: contraction of central pair microtubules.
C: sliding movement of outer doublet microtubules.
D: contraction of outer doublet microtubules.
答案: 【 sliding movement of outer doublet microtubules.】

5、单选题：
‎​Which of the following are characteristics common to all three cytoskeletal systems (microfilaments, microtubules and intermediate filaments)?‎‎
选项：
A: are reorganized during mitosis.
B: have attachment sites for motor proteins.
C: are highly dynamic.
D: possess inherent polarity.
答案: 【 are reorganized during mitosis.】

6、单选题：
 Poleward movement of chromosomes during anaphase A require​
选项：
A: microtubule polymerization.
B: ATP.
C: kinetochore motor proteins.
D: BimC.
答案: 【 kinetochore motor proteins.】

7、判断题：
MAP2 and Tau are examples of microtubule stabilizing proteins.​
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
‌Both colchicine and taxol act to block microtubule assembly, therefore they can arrest cells at metaphase at low dosage.‎
选项：
A: 正确
B: 错误
答案: 【 错误】

9、判断题：
‏Other microtubule plus-end tracking proteins may use EB1 to “hitchhike” onto